Reports, vol. viii., p. 52, Dr. ADDISON’S last case; Dr. ALDIS.

prostration, loss of appetite, nausea, and vomiting; dribbling of urine; last days of life, delirium and slight convulsions.

soles of feet; colour most intense over joints of hands and feet; no definite patches; a little pigment on lips.

interspersed with some grey and translucent substances; no trace of original tissue.

solitary glands very distinct.

90.
Dr. HAYDEN, Dublin Quarterly Journal of Science, Feb.-May, 1865.

Male, 16.

None given. Illness, six months; three weeks in hospital.

Headache for several months; severe pain in abdomen; languor and loss of appetite; heart’s action feeble, sight dim, and respiration hurried on the slightest movement; frequent sickness last ten days of life; death from exhaustion.

On admission, face deep olive, with darker patch on forehead, which had appeared when headache commenced; general surface of body less discolored; minute brown spots visible on abdomen; conjunctivæ pearly white.

Both much enlarged, hard, and nodulated; left capsule much larger than right, and presented the appearance of pale cheese, with about a tea-spoonful of thick, white puriform matter in centre; right capsule not divided.

All healthy; body much wasted.

91.
Dr. WILKS, Guy’s Hosp. Reports, vol. xi., 1865, Dr. STRANGE, Worcester.

Male, 26.

None given. Illness, eighteen months.

Debility; partial loss of appetite; no vomiting; at last delirium, and death from exhaustion.

Eighteen months before death, bronzing slight, in patches; six months later, bronzing well marked all over face and hands, line across forehead very distinct; rest of body clear.

Right capsule described by Dr. Strange as large and distended with pus, the left smaller, and commencing to degenerate; one capsule, examined by Dr. Wilks, was enlarged and converted into a mass of cheesy consistence, with some cretaceous matter, the envelope enclosing it being much thickened.

Every other organ remarkably healthy; no emaciation; half-an-inch of fat on abdomen.