ing. Illness, seven months.

tremely small and feeble, vomiting of mucus containing altered blood, pain in left epigastric region; great depression; constant tendency to sickness.

some parts, irregular superficial abrasions; brain, lungs, and all other organs normal.

94.
Dr. WILKS, Guy’s Hosp. Reports, vol. viii., p. 42, Drs ADDISON and HABERSHON.

Male, 32, engine-driver.

Had lived freely, and had suffered from gonorrhea and syphilis; illness and discoloration, nearly three years. Last attack, one month.

Loss of strength and darkening of skin; in hospital two years before death, and left relieved; a month before death took cold and relapsed; pulse and heart feeble; extreme weakness, dizziness, and failure of vision on attempting to walk; no appetite; death rather sudden, from exhaustion.

Skin dark-brown, and of a deeper tinge in axillæ, and at navel, nipples, and scrotum; mucous membrane of gums and mouth stained with patches of a leaden hue; after death, colour greenish-brown, remarkably uniform, except two black specks on face; margin of lips dark.

Right capsule about normal size; left enlarged; structure of both destroyed by a deposit consisting mainly of white brittle cretaceous matter, and of a semi-transparent matter resembling dirty blanc-mange; right capsule was softened in the middle, and contained about a drachm of cream-like fluid; both firmly adherent to surrounding parts. Under microscope, semi-transparent parts seen to consist of amorphous substance, mixed with granules; the yellow friable matter consisted of little else than fatty and cretaceous granules.

Mucous membrane of stomach highly injected, and covered with tenacious mucus, as if a low form of inflammation had existed; Peyer’s patches, and solitary glands at lower end of ileum, remarkably prominent; all other organs healthy.