neck. Illness, six weeks.

skin cool, obstinate constipation; death from exhaustion.

low cheesy masses; no trace of normal tissue.

tough and yellow; other organs healthy.

107.
Mr. G. MACKENZIE BACON, Med. Gazette, vol. xl., p. 132; also, Guy’s Hosp. Reports, vol. viii., p. 48.

Male, 15, plasterer.

Good health till last illness. Illness, about eight months.

Loss of appetite, nausea and debility, then giddiness and pain in head; intervals of improvement; last week of life, prostration, hiccough, and constant vomiting of food; anæsthesia, with pain in extremities; death from sinking.

Skin began to darken soon after first symptoms of illness; after death, body of a dusky olive hue, except part of chest, with deeper brown patches on face, knees, and along spine; scrotum and penis almost black; conjunctivæ pearly white.

Left capsule large; normal structure obliterated; stroma pale, with firm light-yellowish deposits; right capsule of about normal size, studded with smaller deposits of same nature, but evidently older and undergoing degeneration.

Lungs and other organs quite healthy, except fine pleuritic adhesions on right side, and enlargement of mesenteric glands.

108.
Dr. HOUSELEY, Lancet, 1860, vol. ii., p. 8; also, Guy’s Hosp. Reports, vol. viii., p. 53.

Male, 33, farm-labourer.

Gonorrhœa two years before death. Illness more than a year.

Debility, loss of appetite, nausea, occasional vomiting, pain at epigastrium, constipation, pulse and heart-sounds feeble; last few days of life, incessant sickness.

Face and hands brown; colour nearly natural on chest, but much darker over abdomen and thighs; dark ring round umbilicus; penis and scrotum dingy black; skin on section shewed the colouring matter in the rete-mucosum.

The capsule examined consisted of a smooth hard pinkish mass of fibro-albuminous tissue, degenerating in parts; this tissue was found under the microscope to be composed of nucleated fibre; in the midst were some yellow softer masses, resembling what is called scrofulous matter.

Kidneys, liver, and spleen quite healthy; near the surface of liver, some cretaceous masses, probably the remains of old tubercular disease.

109.
Dr. WILKS, Guy’s Hosp.

Male, 25.

None given. Severe illness two days.

Acute eczema of both arms and hands, for which patient took small doses

No discoloration noticed, but darkness on arms after eruption; after death, face

Right capsule twice the natural size, and converted into firm lardaceous ma-

Lungs congested; other organs all healthy; peritoneal