131.
Dr. VAN CORPUT, Brussels, Gazette Hebdomadaire, 1863, p. 493.

Female, 37, house-keeper.

None given. Illness, some months.

Epigastric pains and emaciation; death sudden.

Characteristic brown discoloration, darkest on face, backs of hands, round nipples, in axillæ, and near umbilicus; on gums and palate, small roundish bluish-brown stains.

Both three times the natural size, hard, and nodulated; cortex thickened, and dark-red brown; medullary substance entirely replaced by yellowish tubercular masses from the size of a bean to that of a pea, some of them softening in their centres.

A single hard cretaceous tubercle, the size of a pea, in apex of left lung; numerous small melanotic masses, from the size of a pea downwards, scattered throughout both lungs; pigment in bronchial glands, liver, and grey substance of brain.

132.
Prof. Dr. BUHL, Wiener Med. Wochenschrift, 1860, p. 6. Dr. VOGEL.

Male, 20.

None given.

None mentioned, but a striking general decay of strength.

Whole surface bronzed, but colour deepest on fingers; tongue also stained with brown patches.

Both enlarged, tough, and containing yellow cheesy nodules; left capsule almost entirely transformed into a cheesy mass.

Lungs contained scattered miliary tubercles, and were loaded with pigment; enlarged bronchial glands, and solitary glands of intestine, also dark-coloured; other organs healthy.

133.
M. VIRCHOW, Canstatt’s Jahresbericht, 1859, M. SCHMIDT, Rotterdam.

Male, 23, sailor.

Intermittent fever previous year. Illness some months, followed by discoloration.

Debility, coldness of skin, loss of appetite, vomiting, pains in loins; progressive emaciation and prostration; death from exhaustion.

Face and hands became of a dusky sepia-brown colour, and sepia-coloured stains were found on the neck, in the axillæ, and lumbar regions, which faded gradually into the normal-coloured skin.

Both enlarged and tuberculous, pink softened portions alternating with harder yellow or yellowish-white parts; in left capsule three pea-sized cavities, formed by the softening down of tubercle;

Old tubercle in apices of both lungs; follicles of intestines swollen and thickened; other organs healthy.