the hospital, we were led by the partial discoloration of the skin to anticipate disease of the capsules, one only of which, however, was found to be implicated. It will have been perceived, that in a certain number of the cases already given, either strumous or malignant disease existed in other parts or organs, as well as in the capsules; and of course, in the midst of such complications, there is often more or less difficulty in satisfactorily unravelling the case in all its details during life; nevertheless as we know, that without any such complications whatever, mere disease of the capsules themselves has proved sufficient to produce such alarming symptoms and such severe consequences, it cannot with any show of reason be alleged that these peculiar symptoms, when present, arise exclusively from the accidental complication of other organs.