Post-mortem examination.- None was allowed beyond the brain and abdomen. Of the former there was considerable softening, and a large amound of subarachnoid fluid. The kidneys were slightly enlarged, mottled, and in some parts the cortical substance was entirely degenerated into fat. A few tubercles were strewed on the surface. Tubercles were also observed on the spleen and on the peritoneum covering the termination of the ileum. Tubercular deposit was also found in one of the supra-renal capsules.

Case 6.- Another specimen, placed in the museum by Dr. Hodgkin, was from a patient of Dr. Bright. The case is very briefly related in the post-mortem records, and no allusion is made to any interest bestowed upon it by Bright, or even that he witnessed the examination. The specimen affords a well-marked example of the change which occurs in Addison’s disease, of which no doubt it was a case, since there is no other morbid condition mentioned in explanation of the patient’s death. It will be seen that it occurred only a few months previous to the one first related (No. 4), and in both of them the specimens were preserved, showing that due attention was bestowed upon the morbid condition of these organs, although no suspicion seemed to be excited as to its being the cause of death, nor, indeed, as far as I am aware, was anything advanced connecting the symptoms with these organs.

Mary C.___, æt. 38, admitted into Guy’s Hospital under Dr. Bright, October 29th, 1828, and died on November 11th. She complained of pain in the chest, had a cough, and was supposed to be labouring under phthisis.

Post-mortem examination.- The lungs were found to contain tubercles ; but the other organs were healthy, with the exception of the supra-renal capsules, which were enlarged, and occupied by a yellow, adventitious deposit, which in parts was softened down.

In the description there is not sufficient disease mentioned to account for death apart from that discovered in the supra-renal capsules.

Case 7.- The following is as interesting a case as any in the series, and to an unprejudiced mind must constitute, I think, a proof beyond all shadow of doubt as to the truthfulness of Addison’s discovery, since it will be seen that it was one of the first which was observed after the publication of the monograph, and what is deserving of especial notice is that the disease was foretold by the publication of the diagnosis long before it was verified by the death of the patient.

VOL. VIII.

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